blood test to test the viscosity of the blood

Together, these experimental results are helpful in identifying the key determinants for the altered T2DM blood viscosity, which can be used in future studies of the hemorheological disturbances of T2DM patients.īlood is a non-Newtonian fluid that delivers necessary substances-such as nutrients and oxygen-to living cells and removes metabolic waste products ( Popel and Johnson, 2005 Secomb, 2017).

Instead, the elevated blood hematocrit, the enhanced red blood cell (RBC) aggregation induced by the increased plasma fibrinogen level, and the reduced RBC deformation play key roles in the determination of blood viscosity in T2DM. Further, to probe the combined effects of multiple factors (including the HbA 1c and plasma fibrinogen levels) on the altered blood viscosity in T2DM, we regroup the experimental data based on the T2DM blood viscosity values at both the low and high shear rates, and our results suggest that the influence of the elevated HbA 1c level on blood viscosity is quite limited, although it is an important indicator of glycemic control in T2DM patients. Instead, when we investigate the influence of plasma fibrinogen level on the blood viscosity in T2DM subjects, we find that the T2DM blood viscosity is significantly and positively correlated with the plasma fibrinogen level. The experimental data show that the mean values of the T2DM blood viscosity are higher in groups with higher HbA 1c levels, but the correlation between the T2DM blood viscosity and the HbA 1c level is not obvious. Here, we evaluate the relationship between the blood viscosity and HbA 1c as well as plasma fibrinogen levels in patients with T2DM. However, the roles of glycated hemoglobin (HbA 1c) and plasma fibrinogen levels on the elevated blood viscosity in subjects with T2DM at different chronic glycemic conditions are still not clear. An elevated blood viscosity has been demonstrated in patients with Type 2 Diabetes Mellitus (T2DM), which might represent a risk factor for cardiovascular complications. The viscosity of blood is an indicator in the understanding and treatment of disease. 2Department of Engineering Mechanics, Zhejiang University, Hangzhou, China.

1Department of Endocrinology and Metabolism, Ningbo First Hospital, Ningbo, China.Jiehui Sun 1 † Keqin Han 2 † Miao Xu 1 Lujuan Li 2 Jin Qian 2 * Li Li 1 * Xuejin Li 2 *

Blood test to test the viscosity of the blood